IsoMist XR

Extended Range Programmable Temperature Spray Chamber

The IsoMist XR is a compact, convenient and maintenance-free temperature-controlled sample introduction system for all ICP-OES and ICP-MS.

IsoMist XR

Enhanced Performance for ICP-MS and ICP-OES

The IsoMist programmable temperature-controlled cyclonic spray chamber features an improved thermodynamic design providing an extended temperature range and faster cool-down so your ICP application is ready to go sooner.


The IsoMist is a compact, convenient and maintenance-free temperature-controlled sample introduction system for all ICP-OES and ICP-MS. 

Product Features

  • High quality and consistent plating of our coils promotes extended coil life
  • Each coil is supplied on a plastic former ensuring correct dimensions and easier installation
  • Each coil is supplied in a special protective container to ensure correct dimensions are maintained, and the coil arrives corrosion free
  • Correct alignment of the coil with respect to the torch body reduces devitrification of the outer tube
  • Reusable alignment tools ensure correct installation every time. Our CD with Do-It-Yourself instructions saves time
  • Regular replacement of corroded coils reduces the load on the RF generating system
  • Changing corroded coils increases enery transfer, resulting in a more robust plasma and generally higher analytical line intensities
IsoMist-XR Exploded View

Benefits of the IsoMist XR

Improve Analytical Stability

On the IsoMist, the spray chamber temperature is accurately controlled through an improved thermodynamic design using a multi-stage Peltier device. The spray chamber temperature is settable in 1°C increments from -25°C to 80°C guaranteeing optimum conditions for any application. The improved cooling efficiency of the new multi-stage Peltier design means the IsoMist is ready, sooner and the cool-down time is reduced.

Reduce Oxide Formation in ICP-MS

Using the IsoMist spray chamber at sub-ambient temperature on an ICP-MS, the sample is cooled so less water vapor is transferred to the plasma resulting in lower oxide formation and reduced polyatomic interferences - improving accuracy and detection limits.

Temperature on ICP-MS Oxide Ratio
Figure 1. Effect of IsoMist XR Temperature on ICP-MS Oxide Ratio. Data Courtesy of David Jones, ALS Chemex.

Perfect for Volatile Organics

When analyzing volatile organic solvents such as naphtha and gasoline a lower sample introduction system temperature reduces nebulization efficiency avoiding quenching of the plasma from solvent over-loading. With a minimum temperature of -25°C analyzing volatile organic solvents is even easier.

Effect of ICP-OES Spray Chamber Temperature
Figure 2. Effect of ICP-OES Spray Chamber Temperature.

Constant Temperature Improves Analytical Stability

Fluctuations in the lab temperature affect sample viscosity and nebulization efficiency. Maintaining the sample introduction system at a constant and stable temperature improves analytical reproducibility, enhances throughput, and lowers operating costs by reducing the need to re-run samples when a calibration verification check standard (Figure 2.) drifts outside the acceptable upper or lower limits.

Effect of IsoMist XR on signal stability
Figure 3. Effect of IsoMist XR on signal stability at ambient temperature.

Elevated Sample Introduction Temperatures Enhances Sensitivity

The sensitivity for many analyses is enhanced by running the spray chamber at an elevated temperature, which is particularly important for samples with limited volume.

Elegant, Ergonomic Design

The IsoMist XR is an elegant, compact, stand-alone system manufactured from inert materials resistant to attack from acids and solvents commonly used in ICP analysis. By using a Peltier thermo-electric device to maintain the spray chamber temperature, the messy, noisy, and high-maintenance refrigerated, recirculating baths used with jacketed spray chambers are eliminated. The compact design also means the IsoMist XR Programmable Temperature Controlled Spray Chambers are compatible with any ICP-OES and ICP-MS.

Helix CT Diagram

Application Flexibility and Superior Design Innovation

The IsoMist incorporates Glass Expansion's' proven Glass Twister cyclonic spray chamber design. A Quartz Twister and HF resistant, high-purity PFA Tracey design is also available upon request. All of which are easily interchangeable, allowing for application flexibility should sample matrices change. All of Glass Expansion's' cyclonic spray chambers, including the IsoMist feature the Helix CT™ interface. The Helix CT fitting is completely inert and carefully designed to fix the depth of penetration and torque of the nebulizer seal so that the aerosol produced is optimal. The Helix CT interface is also the only true zero-dead volume nebulizer/spray chamber interface providing unmatched washout efficiencies. These design innovations have provided Glass Expansion spray chamber sensitivity gains, reduced washout times and reduced matrix effects not possible with other spray chambers.

Spray Chamber Types

Ordering Information

We have established an IsoMist XR Kit for common ICP-OES and ICP-MS models. Each kit contains the IsoMist module, encapsulated Twister spray chamber, torch interface, and mounting bracket (if required).

Please select the kit to match your ICP from the following:

Part Number Description
KT-1119-XR
IsoMist XR Kit for Agilent® 4100, 4200 MP-AES
KT-1137-XR
IsoMist XR Kit for Agilent® 5000 Series
KT-1103-XR
IsoMist XR Kit for Agilent® 7700, 7800, 8800
KT-1135-XR
IsoMist XR Kit for AJ PlasmaQuant 9000 ICP-OES Series
KT-1012-XR IsoMist XR Kit for PerkinElmer Optima 2/4/5/7/8x00 DV
KT-1147-XR IsoMist XR Kit for PerkinElmer® Avio 200, 500
KT-1024-XR IsoMist XR Kit for PG Instruments ICP5000DV
KT-1141-XR IsoMist XR Kit for Spectro® Blue/Green
KT-2757-XR IsoMist XR Kit for Spectro® ARCOS 3 EOP and SOP
KT-1067-XR IsoMist XR Kit for Shimadzu® ICPE 9800
KT-2749-XR IsoMist XR Kit for Shimadzu® ICPE 9820
KT-1015-XR IsoMist XR Kit for Thermo Scientific™ 6000, 7000 Duo
KT-1021-XR IsoMist XR Kit for Thermo Scientific™ 6000, 7000 Radial
KT-1166-XR IsoMist XR Kit for Thermo Scientific™ PRO
KT-1222-XR IsoMist XR for Radom® MICAP-OES

Customer Comments

(In reference to the IsoMist) We are getting around 40% increased sensitivity over what we had before. Also, the QC recoveries for the problem elements B, Al and Zn seem to be much improved.

In terms of doing multi element analysis on spirit samples the IsoMist has proved itself to be a very useful tool.

The IsoMist has significantly boosted our productivity. It is so stable that I need only run a CCV and CCB at the beginning of the day and then start running samples. No need to restandardize daily.

The equipment works extraordinarily well. Keeping temperature at 5°C the noise drops to half as much as without the IsoMist. There is no problem at all with temperature stability and the signal is twice as much as the one obtained without the IsoMist.

We have all instruments using the Niagara Plus and the IsoMist and have increased efficiencies by up to 40% and over-all quality has also shown improvements, so we are very happy with them.

So far we are very happy with the IsoMist spray chamber. The detection limits are better and the intensities are more stable from run to run.

The IsoMist was a treat because it took the place of the jacketed spray chamber, the heated bath, delivery tubes, and pump. It also eliminated my worries about leaks in my sample chamber. It is a small, neat package.

I would enthusiastically recommend the IsoMist to anyone trying to minimize oxide formation in ICP-MS.