MicroMist™ DC Nebulizer

Glass Expansion's MicroMist™ Direct Connect (DC) nebulizer is ideal for low-flow applications due to its excellent transport efficiency and precision. Backed by industry's tightest tolerances, precision manufacturing, and the proprietary VitriCone™ capillary have driven the MicroMist DC nebulizer to be the worldwide standard nebulizer for low-flow ICP-OES and ICP-MS applications.

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Features of the MicroMist™ DC Nebulizer

Designed for Excellent Transport Efficiency and Precision

The MicroMist micro-uptake glass concentric nebulizer offers high performance for limited sample volumes. It makes routine ICP-MS Hg determinations possible and reduces matrix effects when used with Glass Expansion's Cinnabar spray chamber.

Material: Borosilicate glass
High physical reproducibility ~ 1%
TDS tolerance, typically up to 15%
Highest trasnport efficiency
Low RSD's due to highly accurate construction
Standard available uptake: 0.05, 0.1, 0.2, 0.4, 0.5 & 0.6mL/min

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Design Features

VitriCone™ Sample Channel

Proprietary sample channel is guaranteed uniform from entry point to nebulizer tip and thus resistant to clogging.
Rugged precision-machined borosilicate glass capillary resists vibration and delivers the best possible precision.
Industry's tightest tolerances ensure that each nebulizer will perform to the same high standards as the previous one, physical reproducibility within 1%.

UniFit™ Sample Connector

Slides easily over the sample arm creating an excellent insert seal and provides a zero-dead volume sample connection.
A zero-dead volume connection ensures the fastest washout and highest sample throughput, since there is nowhere for sample to be trapped.

Direct Connection (DC) Gas Line

Inert metal-free argon gas connector.
Reliable ratchet fitting ensures leak-free nebulizer gas connection.
Instrument-specific Direct Connect flexible argon gas line (click here for the DC video installation guide).

The DC nebulizer part number has a prefix specific to each type of gas connector. For example, the prefix "A13-" denotes a connector for the Agilent® 7700/7800/7850/7900/8800/8900, so part number A13-1-UM04X is a MicroMist DC nebulizer configured for direct connection to the Agilent® ICP-MS 7700/7800/7850/7900/8800/8900. (Click here for a full list of available DC gas connectors).

Performance

Enhanced Efficiency

Although the MicroMist nebulizer operates a at lower sample flow rate, the transport efficiency is significantly higher compared to a standard concentric nebulizer. The graph illustrates the relationship between uptake rate and nebulizer efficiency (the percentage of the sample that reaches the plasma as opposed to going down the drain).

At 50 µL/min the MicroMist has a 50% efficiency and therefore injects 25 µL/min into the plasma. On the other hand, a standard 2 mL/min concentric nebulizer has a 2% efficiency, resulting in 40 µL/min of sample injected into the plasma. This means that the MicroMist nebulizer can reduce sample consumption by a factor of 40 and yet the sensitivity is reduced by less than a factor of two. For this reason, the MicroMist is first choice for applications with limited sample volumes.

A sample uptake rate for every low-flow application

With a strong and consistent self-aspiration, the MicroMist nebulizers can be used with or without a peristaltic pump. The MicroMist product line includes models with natural sample uptake rates of 50, 100, 200, 400 and 600 µL/min. When choosing a MicroMist nebulizer, select the model that most closely matches your desired sample flow rate. It is always OK to starve a nebulizer, but you should not exceed the natural sample uptake rate. Need help choosing the best option, contact enquiries@geicp.com for help.

Reduced Interferences

The smaller droplet size of the MicroMist nebulizer has additional analytical advantages, including reduced matrix interferences and a more robust plasma.

Tolerance to High Matrix

Although the MicroMist nebulizer is a low-flow nebulizer, it still provides a relatively high tolerance to total dissolved solids (TDS) at 15%. Providing the ability to handle a wide range of sample types, including challenging samples such as waste water, soil, blood, serum, and urine. For the enhanced tolerance to TDS consider adding an argon humidifier, such as our Elegra (see here).

Recommended Applications

Any ICP-OES and ICP-MS application demanding the highest transport efficiency and precision.
Samples with limited volume, such as biological samples.
Samples of high value, such as precious metals and fine chemicals.
Hazardous or radioactive that are difficult to dispose of.
Any organics and highly volatile organics that are challenging due to plasma instability.
Isotope ratio and single event ICP-MS (single-cell, single particle, and nanoparticle) analysis where precision and efficiency are critical. Applications requiring the highest sensitivity and precision, such as toxic metals in cannabis.

Common Accessories

Nexus™ Universal Nebulizer Connection Kit

Speciation is a technique often coupled with ICP-MS. Glass Expansion's Nexus Universal Nebulizer Connection Kit provides a reliable means of directly connecting the output capillary from an HPLC or LC to the MicroMist DC nebulizer. In combination with the VitriCone capillary of the MicroMist, this provides a zero-dead volume high pressure interface eliminating the chance of peak broadening due to dead volume. The Nexus Universal Nebulizer Connection Kit can also be used with precision syringe delivery systems to provide improved stability of sample delivery to the MicroMist nebulizer.

Part Number	Description
FT-18-8	Nexus™ Universal Connection Kit for all Glass Concentric U-Series or DC nebulizers
FT-16-8-X	Nexus™ Universal Connection Kit for Inert nebulizers

Ordering Information

Find a MicroMist™ nebulizer to suit your ICP-MS or ICP-OES:

Manufacturer	Model
Agilent®	7700, 8800
Agilent®	7800, 7850
Agilent®	7900
Agilent®	8900
Agilent®	5100, 5110, 5800, 5900
Analytik Jena	PlasmaQuant MS Series
Perkin Elmer®	NexION 5000
Perkin Elmer®	NexION 1000, 1100, 2000
Perkin Elmer®	NexION 300, 350
Perkin Elmer®	Avio 200, 500 Series
Shimadzu®	ICPM-8500, ICPMS-2030
Thermo Scientific™	Neoma MC-ICP-MS
Thermo Scientific™	Q, RQ, TQ
Thermo Scientific™	PRO DUO
Thermo Scientific™	PRO Radial

For more instrument models click HERE

Customer Comments

I replaced my cross-flow system with your MicroMist and Cinnabar spray chamber and get much better performance. Also, I am getting the same counts as I was getting on my cross-flow at twice the uptake rate.

Environmental service laboratory - USA

I love my MicroMist nebulizer. It's extremely stable and aspirates exactly 100uL/min. I checked it with a balance. My (other brand) aspirates about 300uL, even though it's supposed to be a 100, and it's not nearly as stable.

University laboratory - USA

I really like the MicroMist nebulizer I bought last year. Works great.

Food laboratory - USA

The MicroMist gives better intensity, RSD and is more robust gas-flowrate-wise.

University - USA

The Glass Expansion nebuliser you refer to in your recent e-mail, is it the MicroMist neb? We've been using this for about 18 months now, and are completely satisfied with it. We get very good RSDs on our isotope ratio measurements, we have very few blockage problems and presently I'm using it coupled to an LC system. As I mentioned earlier the MicroMist neb has given outstanding performance on a range of applications.

Government service laboratory - UK

I would suggest the MicroMist nebulizer + Cinnabar spray chamber from Glass Expansion. I did some work on certification of Hg isotopic reference materials and it worked very well. I used this setup in the self-aspirating mode and gained wash-out times for Hg 10 ng/g (solution) 10 times better than with a usual Crossflow nebulizer

Research institute - Germany

After using a GE MicroMist nebulizer and Cinnibar spray chamber on our ICP-MS for several years with excellent results, I bought the same setup for our new PE 4300 ICP-OES for some applications with very small sample sizes. Sensitivity and precision are the same as with the standard cross-flow/Scott combination. Washout is maybe even better, since the Cinnibar washes out very nicely.

Marine science institute - USA

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